Low-Dose Radiation Therapy (LDRT) for Osteoarthritis
LDRT uses doses much lower than those commonly used to treat cancer. For selected adults with persistent, symptomatic osteoarthritis, it may be considered as a noninvasive option intended to influence inflammation and potentially reduce pain. Research is continuing, results vary, and LDRT is not appropriate for every patient. A consultation is needed to review prior treatments, imaging, health history, expected benefits, uncertainties and possible risks.
Understanding LDRT for Osteoarthritis
Learn what to expect before, during and after treatment, including potential benefits, uncertainties and risks.
Read the Patient Guide →Low-Dose Radiation Therapy for Osteoarthritis: Analysis of Preliminary Outcomes at Scripps Clinic
Ojo et al. · Advances in Radiation Oncology · 2026;11:102107
A retrospective study of 167 patients and 184 treated joints reported decreased pain in 88% of joints at the first follow-up visit.
These preliminary observational findings support further research. The study had no randomized comparison group and could not assess long-term safety.
Read the published study ↗